Patricia is taking an evening stroll aboard the Aurelia when she notices a man ready to jump to his death. As she rushes to stop him, he hands her a piece of paper with the number 2124 written on it and begs her, “save Anna.” Then he vanishes into the Pacific.

Devastated, Patricia feels duty-bound to find Anna. She starts with Cabin 2124, where she and her butler, Jermaine, encounter a foul-mouthed couple who don’t know any Annas, nor do they appreciate her knocking on their door. (Higgs makes artful use of fruit names to blunt the couple’s profanity.) None of the cabins they visit produce the Anna they’re seeking, and Patricia reluctantly accepts she’s done her best.

As the ship docks in Tokyo, Patricia plans to tour the city with two new friends, retired policemen Akamu and Rick. They intend to visit a café where customers can pet owls and join a bus trip to Mount Fuji, but everything changes when Patricia sees the couple in Cabin 2124 pushing their way off the ship, and the chase is on.

What follows is a complicated and frightening journey through Tokyo’s underworld. Aided by taxi driver/medical student Hideki, Patricia and her friends race to find what 2124 means and save the mysterious Anna. Her estranged husband, Charlie, shows up midway and makes an applesauce of himself in the pursuit. However, Jermaine and Barbie, along with Akamu, Rick, and Hideki, know Patricia is doing it again and about to kick some serious apricot.

Tokyo is the backdrop for Patricia’s most adventurous investigation to date, as she pushes herself farther than she ever thought possible. The lady in the Windsor Suite proves not only to her unfaithful rat-banana husband, but to herself, that she’s “strong and powerful and capable and more than that; I felt like I was just getting started.” Indeed she is.